Effects of axial stretch on sarcolemmal BKCachannels in post-hatch chick ventricular myocytes

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Characterization of a newly found stretch-activated KCa,ATP channel in cultured chick ventricular myocytes.

With the use of the patch-clamp technique, five kinds of stretch-activated (SA) ion channels were identified on the basis of their single-channel conductances and ion selectivities in cultured chick ventricular myocytes. Because a high-conductance K+-selective channel predominated among these channels, we concentrated on characterizing its properties mostly using excised inside-out patches. Wit...

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ژورنال

عنوان ژورنال: Experimental Physiology

سال: 2010

ISSN: 0958-0670

DOI: 10.1113/expphysiol.2009.051896